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What is Ampelopsin Reduces Endotoxic Inflammation via Repressing ROS-mediated Activation of PI3K:Akt:NF-κB Signaling Pathways about?

The study investigates the anti-inflammatory effects of ampelopsin, a plant flavonoid, on LPS-stimulated RAW264.7 macrophages. Ampelopsin was found to inhibit the release of pro-inflammatory cytokines and nitric oxide by repressing ROS-mediated activation of the PI3K/Akt/NF-κB signaling pathways. The findings suggest that the anti-inflammatory effects of ampelopsin are due to its ability to interfere with critical signaling mechanisms involved in inflammation.

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PostNL Service

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EN