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The Rapid Increase in Radiation Oncology Consultation and Treatment of the Extreme Elderly and its Independence from Population Growth by Gross, J.; Ennis, R.D.; Homel, P.; Evans, A.; Gliedman, P.; Choi, W.; Hu, K.; Shasha, D.; Harrison, L.B.; Fleishman, S. is a Medicine article available to read on EtoBox.
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from the actual treatment duration to determine the prolongation of treatment. A subset of nineteen patients with a potentially higher risk of local recurrence with if treatment times were prolonged were identified, including non-small cell lung cancer (NSCLC) and squamous cell carcinoma (SCCa) of the head and neck (H&N) or cervix. For this subset, assuming a gamma factor (g) of 2 and a dose lost per day prolongation (D L ) of 0.6 Gy/day, the percent loss of LCT at a prescribed dose equivalent in 2 Gy fractions (EQD2 p ) is given by: % loss LCT = (g [D L x days prolonged] x 100%) / EQD2 p . Results: The median number of days of prolongation among all patients was 9 days (4-47 days). The most frequently missed day was the day after Thanksgiving with 37% of patients missing treatment. Overall, planned holiday breaks were the most common reason for prolongation of therapy with a median of 3 days missed (3-4 days). Among the subset of nineteen patients with NSCLC, SCCa of the H&N or cervix, the median days of treatment prolongation was also 9 days (4-37 days), with a median EQD2 p of 70 Gy (54-70 Gy). Using the above equation, this resulted in a predicted percent loss of LCT of 15%. Co
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- Author
- Gross, J.; Ennis, R.D.; Homel, P.; Evans, A.; Gliedman, P.; Choi, W.; Hu, K.; Shasha, D.; Harrison, L.B.; Fleishman, S.
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)