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Long-term Survival of Infants with Idiopathic Myelofibrosis by Rachel A. Altura; David R. Head; Winfred C. Wang is a Medicine article available to read on EtoBox.

What is Long-term Survival of Infants with Idiopathic Myelofibrosis about?

Idiopathic myelofibrosis can develop in children as well as adults. However, the disease appears to be much more aggressive in adults, being characterized by poor survival rates and a high frequency of malignant transformation. Here, we describe three cases of idiopathic myelofibrosis in infants, two of whom were followed for 16 and 22 years after diagnosis. Neither of these patients required more than minimal supportive care, and both have had spontaneous erythropoietic recovery as early as 2–3 years after diagnosis. There have been no indications of malignant transformation or clinical deterioration. Thus, idiopathic myelofibrosis may have a different pathogenesis and clinical course in infants from adults, requiring a more conservative approach to management.

Who reads Long-term Survival of Infants with Idiopathic Myelofibrosis?

Author

Rachel A. Altura; David R. Head; Winfred C. Wang

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0007-1048)

Published

2000

Language

EN

Field

Medicine (Health Sciences)