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Salmonella Typhi and S almonella Paratyphi prevalence, antimicrobial susceptibility profile and factors associated with enteric fever infection in Bahir Dar, Ethiopia by Amsalu, Tadele (author);Genet, Chalachew (author);Adem Siraj, Yesuf (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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Enteric fever (EF) is caused by __Salmonella enterica__ serovars Typhi (__S__. Typhi) and Paratyphi (__S__. Paratyphi) causing significant health problems in developing countries including Ethiopia**.** Thus present study aimed to determine prevalence and antimicrobial resistance profile of __S__. Typhi and __S__. Paratyphi among EF suspected patients at Felege-Hiwot comprehensive specialized hospital, Bahir Dar, Ethiopia. Hospital based cross-sectional study was conducted from March-to-May 2020. Totally, 150 patients were included conveniently. Data were collected using questionnaires by face-to-face interview. Concurrently, venous blood and stool specimens were collected and processed following standard bacteriological technique. Antimicrobial susceptibility test (AST) was performed by disc diffusion method. Logistic regression was performed to identify factors associated with EF infection. The study indicated 5.3% EF prevalence where __S__. Typhi accounted 75%. __S__. Typhi and __S__. Paratyphi isolates were 100% sensitive to cephalosporins but at least 83.3% showed resistance against chloramphenicol and tetracycline. At least 66.7% of isolates were multidrug resistance (MDR). U

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Author

Amsalu, Tadele (author);Genet, Chalachew (author);Adem Siraj, Yesuf (author)

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)