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Examination of Whewellite Kidney Stones by Scanning Electron Microscopy and Powder Neutron Diffraction Techniques by Michel Daudon; Dominique Bazin; Gilles André; Paul Jungers; Alain Cousson; Pierre Chevallier; Emmanuel Véron; Guy Matzen is a Materials Science article available to read on EtoBox.

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Kidney stones made of whewellite,__i.e.__calcium oxalate monohydrate, exhibit various morphological aspects. The crystalline structure of whewellite at the atomic scale was revisited through a single-crystal neutron study at room temperature using a four-circle automated diffractometer. The possible relationships between the various morphological types of whewellite stones and their structural characteristics were examined at the mesoscopic scale by the use of scanning electron microscopy and at the nanometric scale by powder neutron diffraction. All types of whewellite stones displayed a similar structure at the nanometric scale. However, significant differences were found at the mesoscopic scale. In particular, the crystallites in kidney stones resulting from a genetic hyperoxaluria exhibited a peculiar structure. There was a close relationship between stone morphology and crystallite organization at the mesoscopic level and the effectiveness of extracorporeal shockwave lithotripsy.

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Author

Michel Daudon; Dominique Bazin; Gilles André; Paul Jungers; Alain Cousson; Pierre Chevallier; Emmanuel Véron; Guy Matzen

Publisher

International Union of Crystallography; Blackwell Publishing Inc.; International Union of Crystallography (IUCr) (ISSN 0021-8898)

Published

2009

Language

EN

Field

Materials Science (Physical Sciences)