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Clinical study of XiangShaLiuJunZi decoction combined with S-1 as maintenance therapy for stage III or IV gastric carcinoma and colorectal carcinoma by Hong, Xiao-Cui; Liang, Qi-Lian; Luo, Xing-Bo; Hu, Ke-Hui; Yang, Hai-Xia; Ou, Wen-ting; Zhang, Hui-Jie is a Medicine article available to read on EtoBox.
What is Clinical study of XiangShaLiuJunZi decoction combined with S-1 as maintenance therapy for stage III or IV gastric carcinoma and colorectal carcinoma about?
## Introduction: S-1, a new oral fluorouracil chemotherapeutical drug, has been increasingly used in clinical maintenance after first-line chemotherapy for stage iii or iv gastric carcinoma (gc) and colorectal carcinoma (crc) for its own advantages. xiangshaliujunzi decoction (xsljzd), a classic traditional chinese medicine (tcm) formula with effects of alleviating the adverse reactions of chemotherapy and improving the quality of life of cancer patients has been gradually confirmed, with no more reports about the maintenance therapy mode of combination of chemotherapeutic drugs and tcm. we designed the study of xsljzd combined with s-1 in the maintenance therapy of stage iii or iv gc and crc, and hoped that this research program will go further and comprehensively evaluate its efficacy and safety. ## Objectives: The aim of this study was to determine the efficacy and safety of xsljzd combined with s-1 in the maintenance therapy of stage iii or iv gc and crc. ## Methods: This study is an open, single-center, randomized study. patients with stage iii or stage iv gc and crc will be randomized (1:1) into s-1group, s-1 combined with xsljzd group for 5 years of maintenance therapy. the
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- Author
- Hong, Xiao-Cui; Liang, Qi-Lian; Luo, Xing-Bo; Hu, Ke-Hui; Yang, Hai-Xia; Ou, Wen-ting; Zhang, Hui-Jie
- Publisher
- Lippincott Williams and Wilkins; Elsevier ; Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Elsevier BV; Lippincott Williams & Wilkins Ltd.; Medicine Publishing Company Ltd; Williams & Wilkins; Ovid Technologies (Wolters Kluwer Health) (ISSN 1357-3039)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)