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Antibacterial and hemostatic chitin sponge directly constructed from Pleurotus Eryngii via top-down approach by Yan Fang; Yukai Lin; Yanjing Ou; Linyu Wang; Jiang Chen; Caixia Sun; Yunxiang Wen; Haiqing Liu is a Materials Science article available to read on EtoBox.
What is Antibacterial and hemostatic chitin sponge directly constructed from Pleurotus Eryngii via top-down approach about?
Chitin, the second most abundant polysaccharide on earth, possesses unique characteristics, including biosafety, biodegradability, and procoagulant activity, making it an attractive material for hemostasis. However, the conventional bottom-up construction of chitin-based materials is intricate and time-consuming. In this study, we have developed a top-down strategy to prepare a 3D porous chitin-based hemostatic sponge with exceptional hemostatic properties and antibacterial activity, directly from the spongy Pleurotus eryngii. The top-down method involves deproteinization, in situ quaternization, and tannin acid crosslinking. The obtained sponge has an interconnected microporous structure with high porosity (89.7 ± 3.2 %), endowing it with high water absorption (2047 ± 105 %) and rapid water-triggered shape-memory behavior (< 2 s). The sponge exhibits superior blood coagulant activity and outperforms standard medical gauze, gelatin sponge, and chitosan sponge in both topical artery and non-compressive liver puncture wound. In addition, the sponge exhibited significant antibacterial activity against both gram-positive Staphylococcus aureus and gram-negative Escherichia coli. In summ
Who reads Antibacterial and hemostatic chitin sponge directly constructed from Pleurotus Eryngii via top-down approach?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Yan Fang; Yukai Lin; Yanjing Ou; Linyu Wang; Jiang Chen; Caixia Sun; Yunxiang Wen; Haiqing Liu
- Publisher
- Elsevier BV
- Published
- 2024
- Language
- EN
- Field
- Materials Science (Physical Sciences)