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Can I read Early knee OA definition–what do we know at this stage? An imaging perspective on EtoBox?
Early knee OA definition–what do we know at this stage? An imaging perspective by Xiaojuan Li; Frank W. Roemer; Flavia Cicuttini; Jamie W. MacKay; Tom Turmezei; Thomas M. Link is a Medicine article available to read on EtoBox.
What is Early knee OA definition–what do we know at this stage? An imaging perspective about?
While criteria for early-stage knee osteoarthritis (OA) in a primary care setting have been proposed, the role of imaging has been limited to radiography using the standard Kellgren–Lawrence classification. Standardized imaging and interpretation are critical with radiographs, yet studies have also shown that even early stages of radiographic OA already demonstrate advanced damage to knee joint tissues such as cartilage, menisci, and bone marrow. Morphological magnetic resonance imaging (MRI) shows degenerative damage earlier than radiographs and definitions for OA using MRI have been published though no accepted definition of early OA based on MRI is currently available. The clinical significance of structural abnormalities has also not been well defined, and the differentiation between normal aging and structural OA development remains a challenge. Compositional MRI of cartilage provides information on biochemical, degenerative changes within the cartilage matrix before cartilage defects occur and when cartilage damage is potentially reversible. Studies have shown that cartilage composition can predict cartilage loss and radiographic OA. However, while this technology is most pro
Who reads Early knee OA definition–what do we know at this stage? An imaging perspective?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Xiaojuan Li; Frank W. Roemer; Flavia Cicuttini; Jamie W. MacKay; Tom Turmezei; Thomas M. Link
- Publisher
- SAGE Publications
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)