Opening book details…
Can I read Correlation of Ultrasound Parameter Imaging with Microcirculatory Patterns in Uveal Melanomas on EtoBox?
Correlation of Ultrasound Parameter Imaging with Microcirculatory Patterns in Uveal Melanomas by Ronald H. Silverman; Robert Folberg; H.Culver Boldt; Harriet O. Lloyd; Mark J. Rondeau; Mary G. Mehaffey; Frederic L. Lizzi; D.Jackson Coleman is a Medicine article available to read on EtoBox.
What is Correlation of Ultrasound Parameter Imaging with Microcirculatory Patterns in Uveal Melanomas about?
Previous studies demonstrated a correlation between acoustic backscatter parameters and survival in ocular melanoma. The histologic presence of microvascular networks in ocular melanoma is also associated with death from metastases. This study tests the hypothesis that melanomas grouped on the basis of these microvascular patterns are separable by ultrasound spectrum analysis. We scanned 40 melanomas using a 10-MHz ultrasound unit equipped for digitization of radio frequency data. After enucleation, tumors were sectioned in planes corresponding to the ultrasonographic examination and stained to demonstrate microcirculation. Acoustic spectral parameters were compared between 14 melanomas with a nevuslike microcirculation and 26 with foci of high-risk microvascular structures. Smaller scatterer size, lower acoustic concentration and greater spatial variability were found to correlate with high-risk microvascular patterns and areas of cystic degeneration. We suggest that nonvascular extracellular matrix components associated with microvessels may be responsible for the correlation of acoustic parameters with microvascular pattern and distribution.
Who reads Correlation of Ultrasound Parameter Imaging with Microcirculatory Patterns in Uveal Melanomas?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ronald H. Silverman; Robert Folberg; H.Culver Boldt; Harriet O. Lloyd; Mark J. Rondeau; Mary G. Mehaffey; Frederic L. Lizzi; D.Jackson Coleman
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0301-5629)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Health Sciences)