Can I read Diagnostic Testing for a High-grade Inflammation: Parameter Dynamics and Novel Markers on EtoBox?

Diagnostic Testing for a High-grade Inflammation: Parameter Dynamics and Novel Markers by Christina Hoffmann; Peter Hoffmann; Mathias Zimmermann is a Medicine article available to read on EtoBox.

What is Diagnostic Testing for a High-grade Inflammation: Parameter Dynamics and Novel Markers about?

## Background: The timely detection of severe inflammatory conditions is of great importance for early therapy initiation and the patient's prognosis. the complex humoral and cellular processes involved in inflammation offer many opportunities for diagnostic testing, which are still unused in clinical practice. we investigated the dynamics of four established and two novel potential markers during the onset and resolution of a high-grade inflammation. ## Methods: We retrospectively analyzed c-reactive protein and procalcitonin concentrations, leukocyte and thrombocyte counts, granularity index, and δ-hemoglobin measured in peripheral blood samples of patients undergoing inflammation diagnostics between september 2010 and november 2010. data from a consecutive sample of 53,968 patients were available. ## Results: Trajectories for the parameters' dynamics during the onset and resolution of a high-grade inflammation were calculated with a locally weighted scatter plot smoothing method. the leukocyte count trajectories did not exceed the reference range. ## Conclusions: We were able to elucidate the parameter dynamics with time coordinates rounded to the nearest hour and a follow-up of

Who reads Diagnostic Testing for a High-grade Inflammation: Parameter Dynamics and Novel Markers?

Author

Christina Hoffmann; Peter Hoffmann; Mathias Zimmermann

Publisher

Walter de Gruyter GmbH & Co. KG; Walter de Gruyter GmbH (ISSN 1434-6621)

Published

2014

Language

EN

Field

Medicine (Health Sciences)