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Disease and Economic Burden of Surgery in Desmoid Tumors: a Review by Maria M. Fernandez; Timothy Bell; Brad Tumminello; Shahnaz Khan; Shengfan Zhou; Ana B. Oton is a Economics, Econometrics and Finance article available to read on EtoBox.

What is Disease and Economic Burden of Surgery in Desmoid Tumors: a Review about?

Introduction: Desmoid tumors (DT) are soft-tissue tumors that infiltrate into surrounding structures with ill-defined margins. Although surgery is a potential treatment option, complete excision with negative margins is not often possible, the postsurgery recurrence rate is high, and surgery can result in disfigurement and/or loss of function. Areas covered: We conducted a literature review to assess the burden of surgery in patients with DT, focusing on recurrence rates and functional deficits resulting from surgeries. Since economic data related to DT surgery is lacking, reviews of surgery costs in soft-tissue sarcomas and of general costs of amputations were conducted. Risk factors for DT recurrence after surgery are young age ( 5 cm in greatest diameter), positive resection margins, and history of trauma in the area of the primary tumor. Tumors in the extremities have the highest risk of recurrence (30%-90%). Lower rates of recurrences have been reported when radiotherapy was used after surgery (14%-38%). Expert opinion: Although effective in specific cases, surgery may be associated with poor long-term functional outcomes and higher economic costs. Therefore, it is imperative

Who reads Disease and Economic Burden of Surgery in Desmoid Tumors: a Review?

Author

Maria M. Fernandez; Timothy Bell; Brad Tumminello; Shahnaz Khan; Shengfan Zhou; Ana B. Oton

Publisher

Informa UK Limited

Published

2023

Language

EN

Field

Economics, Econometrics and Finance (Social Sciences)