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Magainin 2 and PGLa in bacterial membrane mimics IV: Membrane curvature and partitioning 1 Introduction 1 Materials and methods 2 Sample preparation 2 Large unilamellar vesicles 2 Peptide partitioning 2 Tryptophan fluorescence 2 Leakage assay 3 Dynamic light scattering 3 MD simulations 3 Peptide-induced membrane curvature stress 3 Curvature sensing by peptides 4 Results 5 Partitioning of L18W-PGLa depends on peptide and lipid concentration and is enhanced in the presence of MG2a 5 MG2a and L18W-PGLa induce and sense membrane curvature 6 Discussion 8 Conclusion 11 Supporting material 12 Author contributions 12 Acknowledgments 12 Declaration of interests 12 References 12
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