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USM vs. CATH: Protein Distance Analysis by Petra Vitez is a document available to read on EtoBox.

The document summarizes and critiques a previous study that used the Universal Similarity Metric (USM) to compare protein structures represented as contact maps. The current study finds that when applying the USM method to a much larger dataset of over 2,800 protein domains, it performs worse than other established protein comparison methods. Specifically, the USM distances show low agreement with the classification of protein domains in the CATH tree, indicating it does not accurately capture protein struc

Author

Petra Vitez

Language

EN