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Antimicrobial peptides from Actinobacteria: Current status and future prospects by Jerrine Joseph; Bhaskaran Abirami; Kaari Manigundan; Venugupal Gopikrishnan; Manikkam Radhakrishnan is a book available to read on EtoBox.

What is Antimicrobial peptides from Actinobacteria: Current status and future prospects about?

Antimicrobial peptides (AMPs) are oligopeptides with five to over a hundred amino acids. AMPs have a broad spectrum of targeted organisms such as bacteria, fungi, viruses, and parasites. Rapid killing effect is the important feature of AMPs which can kill the bacterial cells in seconds after the initial contact with cell membrane. AMPs are also known to enhance the activities of antibiotics through synergistic effects. Members of the phylum actinobacteria are the tremendous source for bioactive natural products notably antibiotics. There are several AMPs reported from actinobacteria. Some important class of AMPs reported from actinobacteria include lipopeptides, diketopiperazines, dimeric peptides, nucleosidyl peptides, thioamide-containing peptides, thiopeptides, lasso peptides, and typical cyclic peptides have been illustrated. Most of the AMPs from actinobacteria are produced from the genus Streptomyces followed by Nocardia, Nocardiopsis, Micromonospora, and others. There are several actinobacterial genera still explored for AMPs. AMPs from actinobacteria mainly exhibited antibacterial activity followed by antifungal and anti-TB activity. There are few studies reported the antip

Author

Jerrine Joseph; Bhaskaran Abirami; Kaari Manigundan; Venugupal Gopikrishnan; Manikkam Radhakrishnan

Publisher

Elsevier

Published

2021

Language

EN