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Complete Inclusion of Bioactive Molecules and Particles in Polydime-thylsiloxane: a Straightforward Process Under Mild Conditions by Faccio, Greta; Cont, Alice; Mailand, Erik; Zare-Eelanjegh, Elaheh; Malini, Riccardo Innocenti; Maniura-Weber, Katharina; Rossi, René Michel; Spano, Fabrizio is a scholarly article available to read on EtoBox.

What is Complete Inclusion of Bioactive Molecules and Particles in Polydime-thylsiloxane: a Straightforward Process Under Mild Conditions about?

By applying a slow curing process, we show that biomolecules can be incorporated via a simple process as liquid stable phases inside a polydimethylsiloxane (PDMS) matrix. The process is carried out under mild conditions with regards to temperature, pH and relative humidity, and is thus suitable for application to biological entities. Fluorescence and enzymatic activity measurements, show that the biochemical properties of the proteins and enzyme tested are preserved, without loss due to adsorption at the liquid-polymer interface. Protected from external stimuli by the PDMS matrix, these soft liquid composite materials are new tools of interest for robotics, microfluidics, diagnostics and chemical microreactors.

Author

Faccio, Greta; Cont, Alice; Mailand, Erik; Zare-Eelanjegh, Elaheh; Malini, Riccardo Innocenti; Maniura-Weber, Katharina; Rossi, René Michel; Spano, Fabrizio

Published

2019

Language

EN