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Can I read Investigation of Partially Myristoylated Carboxymethyl Chitosan, an Amphoteric‐amphiphilic Chitosan Derivative, as a New Material for Cosmetic and Dermal Application on EtoBox?
Investigation of Partially Myristoylated Carboxymethyl Chitosan, an Amphoteric‐amphiphilic Chitosan Derivative, as a New Material for Cosmetic and Dermal Application by Haruyoshi Seino; Naoko Kawaguchi; Yukari Arai; Noriyasu Ozawa; Kazuhiko Hamada; Norio Nagao is a Medicine article available to read on EtoBox.
What is Investigation of Partially Myristoylated Carboxymethyl Chitosan, an Amphoteric‐amphiphilic Chitosan Derivative, as a New Material for Cosmetic and Dermal Application about?
## Abstract ## Background Cationic amphiphilic chitosan derivatives can form polymeric micelles, which are useful cosmetic materials, but they form polyion complexes with anionic polymers, which can cause formulation difficulties. ## Aims This study aimed to evaluate the usefulness of partially myristoylated carboxymethyl chitosan, an amphoteric‐amphiphilic chitosan derivative, as a new material for cosmetics in the absence of a surfactant comprising an anionic polymer. ## Methods An anionic polymer and 1,2‐decanediol (an antimicrobial agent)‐containing partially myristoylated carboxymethyl chitosan nanoemulsified lotion and glabridin (an antimelanogenic agent)‐containing partially myristoylated carboxymethyl chitosan polymeric micelle were prepared using a pressure homogenization method. The release of interleukin‐1α, cell viability, and melanogenesis inhibition was evaluated on a human skin model. Antimicrobial activity was evaluated using agar dilution method. ## Results A mixture of partially myristoylated carboxymethyl chitosan and carboxyvinyl polymer did not form a polyion complex, but it formed a hydrophilic gel. The anionic polymer‐containing partially myristoylated carbox
Who reads Investigation of Partially Myristoylated Carboxymethyl Chitosan, an Amphoteric‐amphiphilic Chitosan Derivative, as a New Material for Cosmetic and Dermal Application?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Haruyoshi Seino; Naoko Kawaguchi; Yukari Arai; Noriyasu Ozawa; Kazuhiko Hamada; Norio Nagao
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1473-2130)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)