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This review discusses the role of protein phosphatases as therapeutic targets in cancer immunotherapy and autoimmune disorders, highlighting the challenges and recent advancements in drug discovery. It emphasizes the identification of selective modulators for phosphatases, particularly focusing on SHP2 and TC-PTP, which have shown potential in clinical trials. The article also explores various phosphatase families and their mechanisms of action, underscoring their significance in regulating immune cell sign

Author

working1030biso

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EN