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Estimating the Cost of Industry Investment in Drug Research and Development: A Review of Methods and Results by Stephanie Rennane; Lawrence Baker; Andrew Mulcahy is a Health Professions article available to read on EtoBox.
What is Estimating the Cost of Industry Investment in Drug Research and Development: A Review of Methods and Results about?
Research and development (R&D) costs factor into considerations of the tradeoffs between prices, intellectual property protection, and incentivizing innovation, all of which can have implications for policy development. Yet, there is little consensus on the actual cost of R&D for new drugs. We review and synthesize papers estimating drug R&D costs incurred by industry. We find a substantial range of per-drug costs, from $113 million to just over $6 billion in 2018 dollars. This range includes estimates covering all new drugs, new molecular entities, and drugs in specific therapeutic classes. The range is narrower—$318 million to $2.8 billion—for estimates of the per-drug cost for new molecular entities. We discuss the data sources, methods, and assumptions used in each study to provide context for the wide range in existing estimates. Differences in definitions, methods, and assumptions lead to large divergences in the main estimates, and the combination of fragmented data sources and different assumptions across studies means that the resulting estimates that can rarely be directly compared. We suggest areas for future research and data collection that would result in more compara
Who reads Estimating the Cost of Industry Investment in Drug Research and Development: A Review of Methods and Results?
It is typically read by researchers, students, and practitioners in Health Professions.
- Author
- Stephanie Rennane; Lawrence Baker; Andrew Mulcahy
- Published
- 2022
- Language
- EN
- Field
- Health Professions (Health Sciences)