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This review discusses the development of anaplastic lymphoma kinase (ALK) inhibitors for treating non-small cell lung cancer (NSCLC), highlighting the evolution from first-generation drugs like crizotinib to third-generation options such as lorlatinib. The article emphasizes the ongoing challenges of drug resistance and the need for new therapeutic strategies, including combination therapies and the exploration of fourth-generation inhibitors currently in clinical trials. It also provides insights into the

Author

rijallulfikrirahmadani

Language

EN