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Bisphenol A as degradation product of monomers used in resin-based dental materials by Siemon De Nys; Radu Corneliu Duca; Philippe Vervliet; Adrian Covaci; Imke Boonen; Marc Elskens; Jeroen Vanoirbeek; Lode Godderis; Bart Van Meerbeek; Kirsten L. Van Landuyt is a Dentistry article available to read on EtoBox.
What is Bisphenol A as degradation product of monomers used in resin-based dental materials about?
## Objective: There is still much debate about the release of bisphenol-a (bpa) from dental materials. therefore, this study aimed to quantify bpa present as an impurity in both bpa-based and non-bpa-based monomers and to evaluate whether these monomers may degrade to bpa upon salivary, bacterial, and chemical challenges. ## Methods: Bpa was determined in three different amounts (1, 2, and 3 μmol) of each monomer (tegdma, udma, mudma, bisgma, bisema-3, -6, -10, -30, bispma, ebpadma urethane, badge, and bisdma). next, the monomers (3 μmol) were immersed in whole human pooled saliva collected from adults, streptococcus mutans (2 × 10 cfu/ml), and acidic (0.1 m hcl), alkaline (0.1 m naoh), and control media. the amount of bpa was quantified using a specific and highly sensitive uplc-ms/ms method including derivatization of bpa by pyridine-3-sulfonyl chloride. ## Results: The monomers bisgma and bisema-3 contained trace amounts (0.0006% and 0.0025%, respectively) of bpa as impurities of their synthesis process. bpa concentrations increased when the monomers bisgma, bisema-3, bisema-6, bisema-10, bispma and badge were exposed to saliva and s. mutans, indicating degradation of a small am
Who reads Bisphenol A as degradation product of monomers used in resin-based dental materials?
It is typically read by researchers, students, and practitioners in Dentistry.
- Author
- Siemon De Nys; Radu Corneliu Duca; Philippe Vervliet; Adrian Covaci; Imke Boonen; Marc Elskens; Jeroen Vanoirbeek; Lode Godderis; Bart Van Meerbeek; Kirsten L. Van Landuyt
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Dentistry (Health Sciences)