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Can I read Polyketides with antimicrobial activities from Penicillium canescens DJJ-1 on EtoBox?
Polyketides with antimicrobial activities from Penicillium canescens DJJ-1 by Jia-Peng Wang; Yan Shu; Sheng-Qi Zhang; Lin-Lin Yao; Bing-Xian Li; Li Zhu; Xiao Zhang; Huai Xiao; Le Cai; Zhong-Tao Ding is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Polyketides with antimicrobial activities from Penicillium canescens DJJ-1 about?
Two undescribed polyketides canecines A-B, one unreported cyclopentenone canecine C, together with 12 known compounds were isolated from an extract of the fungus Penicillium canescens DJJ-1. Their structures were elucidated by detailed analysis of spectroscopic data, NMR calculations with dJ-DP4 or DP4+, and their absolute configurations were further determined by quantum chemical calculations of ECD spectra or X-crystallography. Canecine A was a grisan polyketide featuring a dimethyltetrahydro-4H-furo[2,3-b]pyran. Canecine A exhibited significant inhibitory activity against Candida albicans with an MIC value of 1 μg/mL and showed inhibitory effect on nitric oxide production in LPS-activated RAW264.7 macrophages. These results enrich the structural diversities of polyketides from endophytic fungi.
Who reads Polyketides with antimicrobial activities from Penicillium canescens DJJ-1?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Jia-Peng Wang; Yan Shu; Sheng-Qi Zhang; Lin-Lin Yao; Bing-Xian Li; Li Zhu; Xiao Zhang; Huai Xiao; Le Cai; Zhong-Tao Ding
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)