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Procalcitonin (PCT) is a polypeptide glycoprotein that correlates with the severity of sepsis and is produced in response to bacterial infections, primarily influenced by cytokines TNFα and IL-6. Research indicates that PCT serves as an intermediary in the sepsis cascade rather than a direct initiator, with its levels reflecting the severity and prognosis of sepsis in critically ill patients. Notably, a decline in PCT levels prior to death may indicate a poor prognosis, suggesting that PCT can be a valuable
- Author
- SUSANA ELIZABETH NOLES SUAREZ
- Language
- EN