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Quantitation of bioactive components in infant formulas: Milk oligosaccharides, sialic acids and corticosteroids by Fan Liu; Jan van der Molen; Folkert Kuipers; Sander S. van Leeuwen is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Quantitation of bioactive components in infant formulas: Milk oligosaccharides, sialic acids and corticosteroids about?

Human milk is considered the optimal food for infants with abundant nutrients and bioactive components, which play key roles in infant health and development. Infant formulas represent appropriate substitutes for human milk. There are many brands of infant formula with different ingredient sources and functions on the market. The present study aims to quantify important bioactive components, i.e., milk oligosaccharides (MOS), sialic acids (Sia) and corticosteroids, in different infant formulas and compare these to human milk. In total, 12 different infant formulas available on the Dutch market were analyzed in this study. The concentrations of MOS and Sia were characterized by UHPLC-FLD and LC-MS, while corticosteroids were determined using established UHPLC-MS/MS methods. Among infant formulas, 15 structures of oligosaccharides were identified, of which 2′-Fucosyllactose (2′FL), 3′-Galactosyllactose (3′GL) and 6′-Galactosyllactose (6 ́′GL) were found in all infant formulas. The oligosaccharide concentrations differed between milk source and brands and were 3-5 times lower than in human milk. All infant formulas contained Sia, N-acetylneuraminic acid (Neu5Ac) was dominant in bovine

Who reads Quantitation of bioactive components in infant formulas: Milk oligosaccharides, sialic acids and corticosteroids?

Author

Fan Liu; Jan van der Molen; Folkert Kuipers; Sander S. van Leeuwen

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)