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A meta-analysis on the prevalence of resistance of Staphylococcus aureus to different antibiotics in Nigeria by Christian Kelechi Ezeh; Chibuzor Nwadibe Eze; Marie Esther Uju Dibua; Stephen Chijioke Emencheta is a Medicine article available to read on EtoBox.
What is A meta-analysis on the prevalence of resistance of Staphylococcus aureus to different antibiotics in Nigeria about?
## Background Rapid emergence of multidrug resistant __Staphylococcus aureus__ has resulted to difficulty in treatment of infections caused by such strains. The aim of this meta-analysis study was to determine the pooled prevalence of resistance of __S. aureus__ to different antibiotics in Nigeria. ## Methods Literature search for studies was done using Google scholar, PubMed, Science direct, and African Journal Online. The prevalence of __S. aureus__ resistance to different antibiotics was evaluated using the meta-analysis proportion command in MedCalc software version 20.0 adopting a rand effect model. I^2^ statistic and Egger test in MedCalc was used to evaluate the heterogeneity and the presence of publication bias among studies respectively. ## Results A total of 40, 682 studies were retrieved through the database search of which 98 studies met the study inclusion criteria. Prevalence of resistance of __S. aureus__ to different antibiotics ranges from 13 to 82%. Results showed a very high degree of resistance to penicillin G (82% [95% confidence interval (CI) 61%, 0.96%]), cloxacillin (77% [95% CI 64%, 88%]), amoxacillin (74% [95% CI 66%, 81%]), cefuroxime (69% [95% CI 51%, 85
Who reads A meta-analysis on the prevalence of resistance of Staphylococcus aureus to different antibiotics in Nigeria?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Christian Kelechi Ezeh; Chibuzor Nwadibe Eze; Marie Esther Uju Dibua; Stephen Chijioke Emencheta
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)