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Enhancing Clofazimine Solubility Strategies by maninder mani01 is a document available to read on EtoBox.
The study focused on enhancing the solubility and dissolution of Clofazimine, a poorly water-soluble drug, through novel formulations using solid dispersion and inclusion complexation with hydrophilic carriers. Results showed significant improvements in aqueous solubility, particularly with higher drug-to-carrier ratios, attributed to factors like reduced crystallinity and improved wettability. The findings suggest that these formulation strategies can improve Clofazimine
- Author
- maninder mani01
- Language
- EN