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Can I read Alkaloid Production in Catharanthus Roseus Cell Cultures. XI. Biotransformation of 3′, 4′-Anhydrovinblastine to Other Bisindole Alkaloids on EtoBox?

Alkaloid Production in Catharanthus Roseus Cell Cultures. XI. Biotransformation of 3′, 4′-Anhydrovinblastine to Other Bisindole Alkaloids by James P. Kutney; Barbara Aweryn; Lewis S. L. Choi; Pawel Kolodziejczyk; Wolfgang G. W. Kurz; Kenneth B. Chatson; Friedrich Constabel is a Chemistry article available to read on EtoBox.

What is Alkaloid Production in Catharanthus Roseus Cell Cultures. XI. Biotransformation of 3′, 4′-Anhydrovinblastine to Other Bisindole Alkaloids about?

## Abstract Biotransformation studies of 3′,4′‐anhydrovinblastine **(1)** in __Calharanthus roseus__ cell suspension cultures are reported. A detailed study of one cell line, coded at „916”︁, has revealed that **1** is transformed to the natural bisindole alkaloids leurosine (**2**) and Catharine (**3**) in approximately 25–30 and 9–16% yield, respectively. In 24–48 h, about 40% of **1** is utilized by the cells. Conditions for biotransformation of **1** have not been optimized so the above yields quoted are not final.

Who reads Alkaloid Production in Catharanthus Roseus Cell Cultures. XI. Biotransformation of 3′, 4′-Anhydrovinblastine to Other Bisindole Alkaloids?

It is typically read by researchers, students, and practitioners in Chemistry.

Author
James P. Kutney; Barbara Aweryn; Lewis S. L. Choi; Pawel Kolodziejczyk; Wolfgang G. W. Kurz; Kenneth B. Chatson; Friedrich Constabel
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley (ISSN 0018-019X)
Published
1982
Language
EN
Field
Chemistry (Physical Sciences)

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