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Can I read Effect Of Bmi On Time Within Therapeutic Ptt Range In Weight-based Unfractionated Heparin Infusion Without Dose Capping on EtoBox?
Effect Of Bmi On Time Within Therapeutic Ptt Range In Weight-based Unfractionated Heparin Infusion Without Dose Capping by Heather M. Lyons; Cory Heck; Lionel Issac Picot-Vierra; Lydia Tran; Diana Lemieux is a Medicine article available to read on EtoBox.
What is Effect Of Bmi On Time Within Therapeutic Ptt Range In Weight-based Unfractionated Heparin Infusion Without Dose Capping about?
Background: There is limited data surrounding the safety of standardized weight-based unfractionated heparin (UFH) dosing regimens without a dosing cap in patients with a BMI ≥ 40 kg/m 2 . Studies are conflicting as to whether patients with higher body weights achieve anticoagulation targets more quickly than those with lower body weights, and it is unknown whether there is an association between body weight and time within target partial thromboplastin time (PTT) range. Furthermore, patients with a BMI ≥ 40 kg/m 2 are largely underrepresented across anticoagulation studies. Methods: A retrospective cohort study analyzed 7102 adult patients who received weight-based intravenous UFH for at least 48 hours between January 1, 2018 and December 31, 2019 in a five-hospital health system. Patients were divided into 2 groups: BMI ≥ 40 kg/m 2 and BMI < 40 kg/m 2 . The primary outcome was time within therapeutic PTT range. Secondary outcomes included ICU length of stay, hospital length of stay, in-hospital mortality, bleeding events, and proportion of time above, below and within therapeutic PTT range. Results: Of the 7102 patients included, 6413 (90.3%) had a BMI < 40 kg/m 2 and 689 (9.7%)
Who reads Effect Of Bmi On Time Within Therapeutic Ptt Range In Weight-based Unfractionated Heparin Infusion Without Dose Capping?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Heather M. Lyons; Cory Heck; Lionel Issac Picot-Vierra; Lydia Tran; Diana Lemieux
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)