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Short‐term Results of Computerized Tomographic‐based Transperineal Iodine‐125 Prostate Implantation by Kent Wallner; Jitendra Roy; Michael Zelefsky; Patrick Harrington; Zvi Fuks; Louis Harrison is a Medicine article available to read on EtoBox.

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## Abstract There has recently been a resurgence of interest in iodine‐125 (I‐125) prostate implantation for early stage carcinoma due to the introduction of transrectal ultrasonography (TRUS) or computerized‐tomographic (CT)‐based transperineal techniques. The present study details initial tumor response and morbidity of CT‐based transperineal prostate implantation. Forty‐two patients with clinical stage T1 or T2 prostatic carcinoma had CT‐planned transperineal I‐125 implantation of the prostate and have been followed for 6–47 months (median: 19 months). Thirty‐eight patients had an elevated PSA before implantation (>4.0 ng/ml). A total of 35–73 mCi I‐125 was implanted (median: 48 mCi). At 1 year after implantation, 84% of 29 palpable tumors were no longer palpable. Of 38 patients with an elevated prostate specific antigen (PSA) prior to implantation, 98% returned to normal within 12 months of treatment. In 74% of patients, the PSA value fell to below 1.0 ng/ml within 12 months of implantation. Of 25 patients who were sexually potent prior to implantation, 80% remained potent at 3 years. Four patients developed radiation‐induced rectal ulcerations 9–19 months following implantatio

Who reads Short‐term Results of Computerized Tomographic‐based Transperineal Iodine‐125 Prostate Implantation?

Author

Kent Wallner; Jitendra Roy; Michael Zelefsky; Patrick Harrington; Zvi Fuks; Louis Harrison

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1065-7541)

Published

1993

Language

EN

Field

Medicine (Health Sciences)