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Can I read Galectin-1 and Galectin-3 Expression in Human Bladder Transitional-cell Carcinomas on EtoBox?
Galectin-1 and Galectin-3 Expression in Human Bladder Transitional-cell Carcinomas by Luca Cindolo; Giovanna Benvenuto; Paola Salvatore; Raffaela Pero; Gaetano Salvatore; Vincenzo Mirone; Domenico Prezioso; Vincenzo Altieri; Carmelo Bruno Bruni; Lorenzo Chiariotti is a Medicine article available to read on EtoBox.
What is Galectin-1 and Galectin-3 Expression in Human Bladder Transitional-cell Carcinomas about?
Galectin-1 and galectin-3 are galactoside-binding proteins involved in different steps of tumor progression and potential targets for therapy. We have investigated the expression of these galectins in 38 human bladder transitional-cell carcinomas of different histological grade and clinical stage and in 5 normal urothelium samples. Galectin-1 mRNA levels were highly increased in most high-grade tumors compared with normal bladder or low-grade tumors. Western blot and immuno-histochemical analysis of normal and neoplastic tissues revealed a higher content of galectin-1 in tumors. Galectin-3 mRNA levels were also increased in most tumors compared with normal urothelium, but levels were comparable among tumors of different histological grade.
Who reads Galectin-1 and Galectin-3 Expression in Human Bladder Transitional-cell Carcinomas?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Luca Cindolo; Giovanna Benvenuto; Paola Salvatore; Raffaela Pero; Gaetano Salvatore; Vincenzo Mirone; Domenico Prezioso; Vincenzo Altieri; Carmelo Bruno Bruni; Lorenzo Chiariotti
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)
- Published
- 1999
- Language
- EN
- Field
- Medicine (Health Sciences)