Can I read A2A Receptor Enhances Collagen via AKT on EtoBox?

A2A Receptor Enhances Collagen via AKT by yrrybenko is a document available to read on EtoBox.

What is A2A Receptor Enhances Collagen via AKT about?

The study investigates the role of the adenosine A2A receptor (A2AR) in promoting collagen production by human fibroblasts, revealing that A2AR activation increases collagen types I and III through cAMP and AKT pathways, independent of Smad2/3 signaling. The findings indicate that cAMP levels act as a concentration-dependent switch for collagen synthesis, with physiological levels promoting production while excessive levels inhibit it. This research provides insights into the complex mechanisms of fibrosis

Author

yrrybenko

Language

EN