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Mouse Model for Vitiligo Research by walaa baher is a document available to read on EtoBox.
What is Mouse Model for Vitiligo Research about?
This article presents the first mouse model of vitiligo, an autoimmune skin disease characterized by the destruction of melanocytes by CD8+ T cells, leading to depigmented skin. The model involves genetically engineered mice that retain epidermal melanocytes, allowing for the study of disease induction through the transfer of melanocyte-specific T cells and their activation via a viral vector. Detailed protocols for inducing vitiligo, assessing lesion progression, and analyzing skin samples are provided to
- Author
- walaa baher
- Language
- EN