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The document discusses the management of hypoxia in adults with hemoglobinopathies, particularly sickle cell disease (SCD) and thalassemia, emphasizing the importance of understanding the pathophysiology of hypoxia for effective treatment. It outlines the multifactorial causes of hypoxia, including hypoventilation, diffusion impairment, shunting, and ventilation-perfusion inequality, and presents case studies to illustrate these mechanisms. The authors highlight the need for timely recognition and managemen

Author
tapas pani
Language
EN