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Field Evaluation of a Rapid Immunochromatographic Dipstick Test for the Diagnosis of Cholera in a High-risk Population by Xuan-Yi Wang; M Ansaruzzaman; Raul Vaz; Catarina Mondlane; Marcelino ES Lucas; Lorenz von Seidlein; Jacqueline L Deen; Sonia Ampuero; Mahesh Puri; Taesung Park; GB Nair; John D Clemens; Claire-Lise Chaignat; Minoarisoa Rajerison; Farida Nato; Jean-Michel Fournier is a Medicine article available to read on EtoBox.
What is Field Evaluation of a Rapid Immunochromatographic Dipstick Test for the Diagnosis of Cholera in a High-risk Population about?
## Background Early detection of cholera outbreaks is crucial for the implementation of the most appropriate control strategies. ## Methods The performance of an immunochromatographic dipstick test (Institute Pasteur, Paris, France) specific for __Vibrio cholerae__ O1 was evaluated in a prospective study in Beira, Mozambique, during the 2004 cholera season (January-May). Fecal specimens were collected from 391 patients with acute watery nonbloody diarrhea and tested by dipstick and conventional culture. ## Results The overall sensitivity and specificity of the rapid test compared to culture were 95% (95% confidence interval [CI]: 91%–99%) and 89% (95% CI: 86%–93%), respectively. After stratification by type of sample (rectal swab/bulk stool) and severity of diarrhea, the sensitivity ranged between 85% and 98% and specificity between 77% and 97%. ## Conclusion This one-step dipstick test performed well in the diagnosis of __V. cholerae__ O1 in a setting with seasonal outbreaks where rapid tests are most urgently needed.
Who reads Field Evaluation of a Rapid Immunochromatographic Dipstick Test for the Diagnosis of Cholera in a High-risk Population?
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- Author
- Xuan-Yi Wang; M Ansaruzzaman; Raul Vaz; Catarina Mondlane; Marcelino ES Lucas; Lorenz von Seidlein; Jacqueline L Deen; Sonia Ampuero; Mahesh Puri; Taesung Park; GB Nair; John D Clemens; Claire-Lise Chaignat; Minoarisoa Rajerison; Farida Nato; Jean-Michel Fournier
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2334)
- Published
- 2006
- Language
- EN
- Field
- Medicine (Health Sciences)