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Tumour Length as an Independent Prognostic Factor in Resectable Oesophageal Carcinoma by Vadhwana, B; Zosimas, D; Lykoudis, PM; Phen, HM; Martinou, M; Khoo, D is a Medicine article available to read on EtoBox.

What is Tumour Length as an Independent Prognostic Factor in Resectable Oesophageal Carcinoma about?

## Introduction: Oesophageal longitudinal tumour length has been investigated as a prognostic indicator for disease recurrence and overall survival in resectable oesophageal carcinoma. however, there is conflicting evidence regarding its use in clinical practice. this study aims to assess the prognostic significance of histological tumour length in potentially curative oesophageal resections for cancer. ## Materials and methods: Patients with locally advanced oesophageal carcinoma (squamous or adenocarcinoma) were identified in a single centre between july 2000 and december 2016. patient demographics, tumour characteristics and survival outcomes were assimilated. unifactorial and multifactorial analysis was performed to assess tumour length correlation with oncological outcomes. ## Results: A total of 281 patients were included; 226 (80.4%) male and 55 (19.6%) female, with a median age of 66 years; 39 patients (13.9%) developed local recurrence and 104 (37%) distant metastases. disease progression rate was 44.8% with a median progression-free survival of 21 months and median overall survival of 30 months. median tumour length was 3cm (interquartile range 2-4.5cm). multivariate anal

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Author

Vadhwana, B; Zosimas, D; Lykoudis, PM; Phen, HM; Martinou, M; Khoo, D

Published

2020

Language

EN

Field

Medicine (Health Sciences)