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Occurrence of 4 Dengue Virus Serotypes and Chikungunya Virus in Kilombero Valley, Tanzania, During the Dengue Outbreak in 2018 by Beatrice Chipwaza; Robert David Sumaye; Maja Weisser; Winfrid Gingo; Nicholas Kim-Wah Yeo; Siti Naqiah Amrun; Fredros O Okumu; Lisa F P Ng is a Medicine article available to read on EtoBox.
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## Abstract ## Background Dengue and Chikungunya viruses can cause large-scale epidemics, with attack rates of up to 80%. In Tanzania, there have been repeated outbreaks of dengue fever, the most recent in 2018 and 2019, mostly affecting the coastal areas. Despite the importance of these viruses, there is limited knowledge on the epidemiology of dengue (DENV) and Chikungunya (CHIKV) in Tanzania. This study was conducted to investigate the prevalence of DENV and CHIKV in Kilombero Valley, Tanzania. ## Methods A cross-sectional study was conducted at Kibaoni Health Center in Kilombero Valley, Southeastern Tanzania, in the rainy and dry seasons of 2018. Febrile patients of any age and gender were enrolled from the outpatient department. Blood samples were taken and screened for DENV and CHIKV viral RNA by real-time reverse transcription polymerase chain reaction assays. ## Results Overall, 294 patients were recruited. Most were females (65%), and one-third of patients were aged 14–25 years. DENV and CHIKV were detected in 29 (9.9%) and 3 (1.0%) patients, respectively. DENV was detected across all age groups during both the dry and rainy seasons. Although all 4 DENV serotypes were dete
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- Author
- Beatrice Chipwaza; Robert David Sumaye; Maja Weisser; Winfrid Gingo; Nicholas Kim-Wah Yeo; Siti Naqiah Amrun; Fredros O Okumu; Lisa F P Ng
- Publisher
- Oxford University Press (OUP)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)