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Can I read Frequency of virulence factors in Helicobacter pylori-infected patients with gastritis on EtoBox?
Frequency of virulence factors in Helicobacter pylori-infected patients with gastritis by Loghman Salimzadeh; Nader Bagheri; Behnam Zamanzad; Fatemeh Azadegan-Dehkordi; Ghorbanali Rahimian; Morteza Hashemzadeh-Chaleshtori; Mahmoud Rafieian-Kopaei; Mohammad Hossein Sanei; Hedayatollah Shirzad is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Frequency of virulence factors in Helicobacter pylori-infected patients with gastritis about?
The outcome of Helicobacter pylori infection has been related to specific virulence-associated bacterial genotypes. The vacuolating cytotoxin (vacA), cagA gene, oipA and babA2 gene are important virulence factor involving gastric diseases. The objective of this study was to assess the relationship between virulence factors of H. pylori and histopathological findings. ## Material and methods: Gastroduodenoscopy was performed in 436 dyspeptic patients. antrum biopsy was obtained for detection of h. pylori, virulence factors and for histopathological assessment. the polymerase chain reaction was used to detect virulence factors of h. pylori using specific primers. ## Results: Vaca genotypes in patients infected with h. pylori were associated with caga, icea1 and icea2. in the patients with h. pylori infection there was a significant relationship between caga positivity and neutrophil activity (p = 0.004) and chronic inflammation (p = 0.013) and with h. pylori density (p = 0.034). neutrophil infiltration was found to be more severe in the s1 group than in the s2 group (p = 0.042). also was a significant relationship between oipa positivity and neutrophil activity (p = 0.004) and with h
Who reads Frequency of virulence factors in Helicobacter pylori-infected patients with gastritis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Loghman Salimzadeh; Nader Bagheri; Behnam Zamanzad; Fatemeh Azadegan-Dehkordi; Ghorbanali Rahimian; Morteza Hashemzadeh-Chaleshtori; Mahmoud Rafieian-Kopaei; Mohammad Hossein Sanei; Hedayatollah Shirzad
- Publisher
- Elsevier BV
- Published
- 2015
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)