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Can I read Usefulness of Transient Elastography for Non-Invasive Diagnosis of Liver Fibrosis in Pediatric Non-Alcoholic Steatohepatitis on EtoBox?
Usefulness of Transient Elastography for Non-Invasive Diagnosis of Liver Fibrosis in Pediatric Non-Alcoholic Steatohepatitis by Young Dai Kwon; Kyung Ok Ko; Jae Woo Lim; Eun Jung Cheon; Young Hwa Song; Jung Min Yoon is a Medicine article available to read on EtoBox.
What is Usefulness of Transient Elastography for Non-Invasive Diagnosis of Liver Fibrosis in Pediatric Non-Alcoholic Steatohepatitis about?
## Background Transient elastography (FibroScan^®^) is a non-invasive and rapid method for assessing liver fibrosis. While the feasibility and usefulness of FibroScan^®^ have been proven in adults, few studies have focused on pediatric populations. We aimed to determine the feasibility and usefulness of FibroScan^®^ in Korean children. ## Methods FibroScan^®^ examinations were performed in 106 children (age, 5–15 years) who visited the Konyang University Hospital between June and September 2018. Liver steatosis was measured in terms of the controlled attenuation parameter (CAP), while hepatic fibrosis was evaluated in terms of the liver stiffness measurement (LSM). Children were stratified into obese and non-obese controls, according to body mass index (≥ or < 95th percentile, respectively). ## Results The obese group was characterized by significantly higher levels of aspartate aminotransferase (AST, 57.00 ± 48.47 vs. 26.40 ± 11.80 IU/L; __P__ < 0.001) and alanine aminotransferase (ALT, 91.27 ± 97.67 vs. 16.28 ± 9.78 IU/L; __P__ 95% percentile) (__P__ < 0.001), CAP (244.4–340.98 dB/m), and LSM (3.85–7.77 kPa) (__P__ 5.5 kPa), whereas the remaining 29 did not (LSM < 5.5 kPa). O
Who reads Usefulness of Transient Elastography for Non-Invasive Diagnosis of Liver Fibrosis in Pediatric Non-Alcoholic Steatohepatitis?
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- Author
- Young Dai Kwon; Kyung Ok Ko; Jae Woo Lim; Eun Jung Cheon; Young Hwa Song; Jung Min Yoon
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)