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LD50 of Pseudomonas Exotoxin A in Mice by Yudha Pradhana Putra is a document available to read on EtoBox.
1) The study determined the lethal dose (LD50) of exotoxin A produced by Pseudomonas aeruginosa strain 26A in mice through injection of varying concentrations and observation of mortality over 5 days. 2) The LD50 of purified exotoxin A was found to be 1 μg/ml, as concentrations at or above this level resulted in over 50% lethality in mice. 3) Histopathological examination of liver, spleen, and kidney tissues from mice injected with higher exotoxin A doses showed significant degeneration including necrosi
- Author
- Yudha Pradhana Putra
- Language
- EN