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Can I read A Review of the Impact of Neoadjuvant Chemotherapy on Breast Surgery Practice and Outcomes on EtoBox?
A Review of the Impact of Neoadjuvant Chemotherapy on Breast Surgery Practice and Outcomes by Niamh O’Halloran; Aoife Lowery; Catherine Curran; Ray McLaughlin; Carmel Malone; Karl Sweeney; Maccon Keane; Michael Kerin is a Medicine article available to read on EtoBox.
What is A Review of the Impact of Neoadjuvant Chemotherapy on Breast Surgery Practice and Outcomes about?
## Introduction: Neoadjuvant chemotherapy (nac) is increasingly used in locally advanced breast cancer as it facilitates breast conserving surgery (bcs) and allows surgical treatment of patients considered inoperable at baseline. the aim of this study was to assess the trends in breast cancer management with regard to the administration of nac and adjuvant chemotherapy and the effect this has on surgical practice, patient outcomes, and patterns of disease recurrence. ## Patients and methods: Patients treated with chemotherapy from 2005 to 2014 were identified from a prospectively maintained database. clinicopathologic details, timing of chemotherapy delivery, and surgical procedures carried out were analyzed. ## Results: A total of 1619 patients were included in the study. the nac group (n = 383) had a higher t stage (p < .001) and higher grade disease than the adjuvant group (p = .017). luminal a breast cancer was less likely to be treated by nac. the proportion of patients treated with nac has increased from 12.1% in 2005 to 48.3% in 2014 (p < .001). there was an increase in the bcs rate over time (p = .002); however, a higher proportion of the neoadjuvant group (55.5%) underwent
Who reads A Review of the Impact of Neoadjuvant Chemotherapy on Breast Surgery Practice and Outcomes?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Niamh O’Halloran; Aoife Lowery; Catherine Curran; Ray McLaughlin; Carmel Malone; Karl Sweeney; Maccon Keane; Michael Kerin
- Publisher
- CIG Media Group, LP.; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 1526-8209)
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)