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Specific Features of Differentiated Thyroid Carcinoma in Patients Over 70 Years of Age by G.C. Biliotti; F. Martini; V. Vezzosi; P. Seghi; F. Tozzi; A. Castagnoli; G. Basili; A. Peri is a Medicine article available to read on EtoBox.

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## Abstract ## Background and Objectives Among the geriatric population, there is a lower incidence of thyroid carcinoma (TC), but it accounts for 30% of all thyroid disorders compared to 6–8% in younger subjects. Prognosis, moreover, is worse in the elderly, as demonstrated by the fact that 81% of deaths related to these tumors occur in patients over 55. The aim of this retrospective study was to identify the characteristics of differentiated thyroid carcinoma (DTC) peculiar to the elderly. ## Methods Of 638 patients who underwent surgery for DTC over a period of 30 years, 46 were more than 70 years old. All the elderly patients had undergone radioioidine and TSH‐suppression therapy following surgical resection. ## Results and Conclusions Despite these measures, the rate of recurrence was 26.5% at 5 years and 63.6% at 10 years. The 5‐ and 10‐year disease‐specific survival rates were 87.8% and 63.6%, respectively. On an average, survival was 55.1 months when death was disease‐related, and with regard to histological type, it was longer in papillary carcinoma than in the follicular variant, and longest of all in occult sclerosing carcinoma. Survival was greatest in patients with tum

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Author

G.C. Biliotti; F. Martini; V. Vezzosi; P. Seghi; F. Tozzi; A. Castagnoli; G. Basili; A. Peri

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-4790)

Published

2006

Language

EN

Field

Medicine (Health Sciences)