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Biotransformation of (RS)-reticuline and morphinan alkaloids by cell cultures of Papaver somniferum by Tsutomu Furuya; Masao Nakano; Takafumi Yoshikawa is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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RS)-Reticuline was stereospecifically converted to (-)-(S)-scoulerine and (-)-(S)-cheilanthifoline by cell cultures of Pupaver sornnijerurn and (-)-(R)-reticuline was recovered as an optical pure compound by racemic resolution. (-)-Codeinone was converted in high yield to (-)-codeine in both cell culture and enzyme preparation, but the other morphinans, thebaine, codeine and morphine, were not metabolized.

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Author

Tsutomu Furuya; Masao Nakano; Takafumi Yoshikawa

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0031-9422)

Published

1978

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)