Opening book details…
Can I read Analyzing Outcome-based Staging for Clinically Localized Adenocarcinoma of the Prostate on EtoBox?
Analyzing Outcome-based Staging for Clinically Localized Adenocarcinoma of the Prostate by Anthony V. D'Amico; April Desjardin; Ming-Hui Chen; Steve Paik; Delray Schultz; Andrew A. Renshaw; Kevin R. Loughlin; Jerome P. Richie is a Medicine article available to read on EtoBox.
What is Analyzing Outcome-based Staging for Clinically Localized Adenocarcinoma of the Prostate about?
## Background: A clinical staging system based on the prostate-specific antigen (psa) and the calculated prostate carcinoma volume (cvca) construct previously has been proposed. this study was performed to assess whether this proposed clinical staging system was valid in an independent surgical and radiation data set in patients with clinically localized disease. ## Methods: Cox regression multivariable analyses were used to assess the significance of staging systems (1992 american joint commission on cancer staging [ajcc] clinical and pathologic stage, versus cvca-psa clinical stage) to predict time to posttherapy psa failure in 441 and 465 patients managed by surgery and radiation, respectively. significant staging systems identified using cox regression were tested further using established comparative measures to define the most clinically useful system. ## Results: Both the 1992 ajcc pathologic stage and the cvca-psa clinical stage were significant predictors of time to postoperative psa failure (p = 0.0001), whereas only the cvca-psa clinical stage was a significant predictor of time to postradiation psa failure (p = 0.0001) using a cox regression multivariable analysis. furt
Who reads Analyzing Outcome-based Staging for Clinically Localized Adenocarcinoma of the Prostate?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Anthony V. D'Amico; April Desjardin; Ming-Hui Chen; Steve Paik; Delray Schultz; Andrew A. Renshaw; Kevin R. Loughlin; Jerome P. Richie
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)
- Published
- 1998
- Language
- EN
- Field
- Medicine (Health Sciences)