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Primary stent implantation is superior to balloon angioplasty in acute myocardial infarction: Final results of the primary angioplasty versus stent implantation in acute myocardial infarction (PASTA) trial by Shigeru Saito; George Hosokawa; Shinji Tanaka; Sunao Nakamura; for the PASTA Trial Investigators is a Medicine article available to read on EtoBox.

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Several studies have shown that stent implantations in acute myocardial infarction (AMI) result in better short-and long-term outcomes than primary balloon angioplasty. These results, however, have not been ascertained in randomized trials. We randomized 136 patients out of 208 patients with AMI within 12 hr from onset into two groups: 69 patients with primary balloon angioplasty (POBA group) and 67 patients with primary stent implantation (STENT group). We compared the incidences of major cardiac events (repeat MI, target lesion revascularization, and cardiac death) and angiographic parameters during hospitalization and follow-up periods up to 12 months in these two groups. There was no significant difference in the reperfusion success rates. The incidences of major cardiac events were lower in the STENT group than in the POBA group during hospitalization, the first 6 months and 12 months (6% vs. 19%, P ‫؍‬ 0.023; 21% vs. 46%, P F 0.0001; 22% vs. 49%, P ‫؍‬ 0.0011). Minimum lumen diameters were significantly bigger in the STENT group than the POBA group at predischarge angiogram and 6-month follow-up (2.85 ؎ 0.62 vs. 2.08 ؎ 0.82 mm, P F 0.0001; 2.24 ؎ 0.64 vs. 1.72 ؎ 0.76, P ‫؍‬ 0

Who reads Primary stent implantation is superior to balloon angioplasty in acute myocardial infarction: Final results of the primary angioplasty versus stent implantation in acute myocardial infarction (PASTA) trial?

Author

Shigeru Saito; George Hosokawa; Shinji Tanaka; Sunao Nakamura; for the PASTA Trial Investigators

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1522-1946)

Published

1999

Language

EN

Field

Medicine (Health Sciences)