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What is Anti-HIV Activity of Tricaffeoylquinic Acid about?

The study investigates the anti-HIV activity of 3,4,5-tricaffeoylquinic acid (TCQA) isolated from cultured lettuce cells, demonstrating its potent inhibitory effects on HIV-1 integrase with an IC50 of 0.063 µM. TCQA showed the highest anti-HIV activity compared to other caffeoyl derivatives, with minimal cell toxicity at 18.4 µM. This research suggests potential for TCQA in developing new HIV treatment options.

Author

nguyenthituongvi2020.gr

Language

EN