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This study conducted active surveillance for avian influenza viruses in live poultry markets and wetlands in Bangladesh from 2018 to 2019, revealing distinct viral activities in both environments. Predominant virus subtypes included low pathogenic avian influenza H9N2 and highly pathogenic avian influenza H5N1, with a notable turnover of H5N1 genotypes in live poultry markets. The findings highlight the complex dynamics of viral evolution and the interconnectedness of the two environments despite their dist

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