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Serum D-dimer changes and prognostic implication in 2009 novel influenza A(H1N1) by Z.F. Wang; F. Su; X.J. Lin; B. Dai; L.F. Kong; H.W. Zhao; J. Kang is a Medicine article available to read on EtoBox.

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## Background: The patients with influenza a (h1n1) have a higher mortality compared with suffering from seasonal influenza. however, many clinical characteristics are still not clear. in the course of clinical treatment on h1n1, we found there were some apparent abnormal clinical indexes being detected at the preliminary diagnosis for severely ill patients, especially the obvious increasing of d-dimer. d-dimer may be associated with the prognosis of influenza a (h1n1). ## Methods: Patients' clinical data (age, gender, body mass index, primary diseases, etc.) and the preliminary diagnostic clinical indexes including blood creatine kinase (ck), creatine kinase isoenzyme (ck-mb), lactic dehydrogenase (ldh), t cell subsets, blood gas analysis, d-dimer, activated partial thromboplastin time (aptt), prothrombin time (pt) and plasma fibrinogen (fg) were retrospectively analyzed. ## Results: Compared with the non-respiratory failure group, the cases in respiratory failure group, especially in death sub-group have lower lymphocytes, higher ldh and d-dimer, as well as decreasing oxygenation index during the preliminary diagnosis(p<0.05). the disease severity (apche ii scores) was independen

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Author

Z.F. Wang; F. Su; X.J. Lin; B. Dai; L.F. Kong; H.W. Zhao; J. Kang

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0049-3848)

Published

2011

Language

EN

Field

Medicine (Health Sciences)