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DADA2: Enhanced Amplicon Error Correction by Jocilene Dantas Torres Nascimento is a document available to read on EtoBox.
What is DADA2: Enhanced Amplicon Error Correction about?
DADA2 is an open-source R package that improves upon the DADA algorithm for modeling and correcting errors in Illumina-sequenced amplicon data. It implements a new quality-aware model of Illumina errors and infers sample composition by dividing reads into partitions consistent with the error model. When tested on mock communities with varying diversity and sequencing quality, DADA2 identified more true variants and output fewer spurious sequences than other leading methods such as UPARSE, MED, mothur, and Q
- Author
- Jocilene Dantas Torres Nascimento
- Language
- EN