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Comparison of Cytocompatibility of Zein Film with Other Biomaterials and Its Degradability in Vitro by Qing‐Shen Sun; Jian Dong; Zhi‐Xin Lin; Bin Yang; Jin‐Ye Wang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Abstract Cytocompatibility of particle zein (Pzein) and film zein (Fzein) was evaluated and compared with polyhydroxybutyrate (PHB), its copolymer poly(hydroxybutyrate‐co‐hydroxyvalerate) (PHBV), polylactic acid (PLA), and collagen, using HL‐7702 cells, in terms of cell attachment rate within 3 h, and cell viabilities at 3 and 6 days determined by the 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl tetrazolium bromide (MTT) method. The zein degradation test was carried out using collagenase and trypsin, and the degradation product was added to the culture medium at different concentrations in order to examine the concentration‐dependent cytotoxic effect. Result: The adhesion rate of the HL‐7702 cells on both Pzein and Fzein was higher than that on collagen film. Cell viabilities were higher on both Pzein and Fzein than on films of PLA, PHB, PHBV, and collagen from fish skin. Zein can be degraded by both trypsin and collagenase, and the degradation product can enhance cell viability within a certain range of concentrations. © 2005 Wiley Periodicals, Inc. Biopolymers 78: 268–274, 2005

Who reads Comparison of Cytocompatibility of Zein Film with Other Biomaterials and Its Degradability in Vitro?

Author

Qing‐Shen Sun; Jian Dong; Zhi‐Xin Lin; Bin Yang; Jin‐Ye Wang

Publisher

Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0006-3525)

Published

2005

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)