Can I read Growth in Children With End-Stage Kidney Disease on EtoBox?

Growth in Children With End-Stage Kidney Disease by Emily Stonebrook; Rose Mary Ayoob; John D. Mahan is a book available to read on EtoBox.

What is Growth in Children With End-Stage Kidney Disease about?

Growth is a complex process dependent on adequate nutrition and interconnected metabolic and endocrine pathways; growth failure is one of the most common and important complications seen in children with chronic kidney disease (CKD). Advances in understanding the crucial role of nutrition and the growth hormone-insulin-like growth factor-1 (GH/IGF-1) axis has continued to expand. Moreover, CKD clinical manifestations can be highly variable, including fluid/electrolyte abnormalities, metabolic acidosis, abnormal bone metabolism, and malnutrition, all of which can significantly affect growth. Different medical interventions and renal replacement therapy can also impact growth and development. Children receiving kidney transplants and/or treatment with recombinant human GH (rhGH) show better mean final height than those who continue on long-term dialysis and/or did not receive concomitant rhGH therapy. Young age at end-stage kidney disease (ESKD) onset, severity and duration of renal failure, male gender, and presence of congenital nephropathies are the most relevant risk factors for decreased final adult height. The multifactorial pathogenesis of growth failure in children with CKD c

Author

Emily Stonebrook; Rose Mary Ayoob; John D. Mahan

Publisher

Elsevier

Published

2023

Language

EN