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This document describes the synthesis of sulfanilamide through three stages: 1) the chlorosulfonation of acetanilide producing 4-acetamidobenzenesulfonyl chloride, 2) the nucleophilic substitution of this compound by ammonia producing sulfonamide, and 3) the acid hydrolysis of the sulfonamide producing sulfanilamide. The yield of the reaction was 50.63%.

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